Ventral tegmental area cholinergic mechanisms mediate behavioral responses in the forced swim test
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چکیده
منابع مشابه
Segregated cholinergic transmission in the ventral tegmental area
Dopamine neurons in the ventral tegmental area (VTA) receive cholinergic innervation from brainstem structures associated with either movement or reward. While cholinergic neurons of the pedunculopontine nucleus (PPN) carry an associative/motor signal, those of the laterodorsal tegmental nucleus (LDT) convey limbic information. Here we used optogenetic methods combined with in vivo juxtacellula...
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Tobacco use is a major health problem that is estimated to cause 4 million deaths a year worldwide. Nicotine is the main addictive component of tobacco. It acts as an agonist to activate and desensitize nicotinic acetylcholine receptors (nAChRs). A component of nicotine's addictive power is attributable to actions on the mesolimbic dopaminergic system, which serves a fundamental role in the acq...
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Methylphenidate (MPD) is a psychostimulant used in the treat treatment of attention deficit hyperactivity disorder and more recently is being used as a cognitive enhancement and recreational drug. Its therapeutic effects are not fully understood, nor are the long term effects of the drug on brain development. The ventral tegmental area (VTA) is a site of psychostimulant action thought to be inv...
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ژورنال
عنوان ژورنال: Behavioural Brain Research
سال: 2015
ISSN: 0166-4328
DOI: 10.1016/j.bbr.2015.04.002